Essential R&D knowledge from the leader in predictive biosimulation

Thomson Reuters is able to supply exclusive Target reports from Entelos Inc, the leader in predictive biosimulation, including specially-compiled custom reports for your own lead compounds.

Entelos develops computer models of human physiology, employing its unique PhysioLab^® technology to create sophisticated ‘virtual patients’ that accurately predict the effects and efficacy of candidate drugs and can also give indications on liability and toxicology.

Based on manual analysis of thousands of peer-reviewed journal articles, constantly updated, and representative of the disease population, these ‘virtual patients’ can provide quick, cost-effective predictive modeling for a wide variety of diseases.

In each available therapy area, the Entelos Target reports condense the company’s simulation data and results into knowledge essential for all organizations and scientists involved in pharmaceutical and biotechnology research and development.

Users of Thomson Pharma can access the standard reports via the solution’s browse and search functions (a separate subscription is required).

Available report types

Discovery report
For your chosen therapy area, this report indicates how hard you need to hit a target to ensure the efficacy of a candidate drug. It provides a unique perspective to help focus your discovery efforts, increase efficiency, and aid in developing new hypotheses.

Clinical report
For your chosen therapy area, this report indicates the optimal compound characteristics of a candidate drug (how much to give, how to measure its effects). It is compiled especially for those responsible for advancing compounds into clinical trials. By modeling long-term clinical trials, it can help you to determine which patient subgroups will benefit most.

Commercial report
For your chosen therapy area, this report indicates how good a candidate drug needs to be in order to achieve approval and market share. It enables you to differentiate your compound in the market, and helps to identify potential risks and liabilities.

Custom report
We can create a tailored, specially-compiled report for your own lead compounds. By generating your own custom report, you can gain novel insights into how your drug performs against the market leaders.

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